Neuro and pineal
Semax
Also listed as ACTH(4-7)-Pro-Gly-Pro
ACTH(4–7) analogue heptapeptide
- BDNF / TrkB
- Formula
- C37H51N9O10S
- Molar mass
- 813.92 g/mol
- CAS number
- 80714-61-0
Identity
What the molecule is, from its PubChem record. These are the figures a certificate of analysis should agree with.
- Class
- ACTH(4–7) analogue heptapeptide
- Sequence
H-MEHFPGP-OH
- Seven residues: the ACTH(4–7) fragment Met-Glu-His-Phe, followed by Pro-Gly-Pro.
- Molecular formula
- C37H51N9O10S
- Molar mass
- 813.92 g/mol
- CAS number
- 80714-61-0
- PubChem
- CID 9811102
Checked against PubChem on 27 September 2026. Molar mass is calculated from the formula with standard atomic weights and agrees with PubChem’s published molecular weight. In sequences, H- marks a free N-terminus, -OH a free C-terminal acid and -NH₂ a C-terminal amide.
Research context
Semax is a heptapeptide made of the ACTH(4–7) fragment Met-Glu-His-Phe followed by Pro-Gly-Pro, a tail that slows enzymatic breakdown. In neuronal cell and brain-tissue models it is studied for expression of brain-derived neurotrophic factor (BDNF) and signalling through its receptor, TrkB.
Research use only. Everything on Vialwise concerns research-grade material sold for laboratory and analytical use only. It is not a registered medicine, is not supplied for human or veterinary use, and nothing here is medical advice.
Storage and handling
Store sealed lyophilised powder at −20 °C, dry and away from light.
Let the vial reach room temperature before opening, so moisture doesn’t condense on the powder.
Reconstitute in sterile water, or in the buffer your protocol specifies. Swirl gently rather than shake.
Contains methionine, which oxidises in air. Keep headspace small and time in solution short.
Split the solution into single-use aliquots and keep them frozen, so no portion goes through repeated freeze–thaw.
General laboratory practice for this class of material; your institution’s own procedures come first. To work out concentration and aliquot volumes from a vial’s mass, use the reconstitution calculator. For the reasoning behind each step, read storing lyophilised peptides.
Published lab reports
Lab reports for Semax at Au Peptide Labs Our store
The one supplier whose full report list we have.
Open each lab-linked report on the lab’s own website to confirm it.
- Lab link
Semax 10mg
Task #157236Added 11 Aug 2026
Verify at janoshik.com98.724%purity
Other suppliers publish their reports on their own sites. Where each supplier publishes its COAs
Vialwise is published by APL Research Pty Ltd, which also runs Au Peptide Labs. Every supplier, ours included, is scored on the same published checklist. How we handle this
Any supplier
Check any supplier’s Semax COA
These checks take a few minutes and work the same on a report from any supplier, ours included. The walkthrough shows each one on a real Janoshik report.
How to verify a Janoshik COAOpen it at the lab
The report should load on the testing lab’s own website from the verify link or task number, not only as a PDF or screenshot from the supplier.
Match the name
The sample should be named Semax or ACTH(4-7)-Pro-Gly-Pro, or a clear equivalent. A different compound name means a different report.
Match the mass
If the report includes a mass-spectrometry result: a deconvoluted average-mass result should sit close to 813.92 g/mol; high-resolution reports give the slightly lower monoisotopic mass, and raw spectra show m/z for charged ions (mass ÷ charge). How HPLC and mass spec work.
Match the vial
The sample amount on the report should match the vial size you’re buying. A report on a different size or an older batch tells you less about the vial in front of you.
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